A brief overview of the mechanisms of action by which traditional and next-generation probiotics affect host health

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Probiotics have a range of documented effects on human health, with hundreds of studies from the past several decades showing their ability to alter physical or behavioural phenotypes in humans. These human efficacy trials provide the necessary evidence to guide probiotic use. In designing a trial, however, the researchers often wonder how to select the best strain for the task in order to increase the likelihood of success

 

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